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No. Glucose-Fructose Syrup (GFS) or Fructose-Glucose Syrup (FGS) – sometimes referred to as Isoglucose or HFCS – like all simple sugars, are carbohydrates, and all carbohydrates have the same caloric value of 4kcal/g.

This means that Glucose Fructose Syrups or Fructose Glucose Syrups are no more – or less – caloric than any other type of simple sugar.